Journal of Pediatric Neurology and Neuroscience

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Review Article Pages 233-236

Rhythmic High-Amplitude Delta with Superimposed Spikes (RHADS): A Treatment Dilemma

Authors: Vanita Shukla, MD, Paul Webb, MD, Bashayer AlMohaimeed, MD, James Lee, MD and Cyrus Boelman, MD

Abstract: Rhythmic High-Amplitude Delta Activity with Superimposed (poly)spikes (RHADS) is a pathognomonic electroencephalography (EEG) signature that may facilitate the recognition of Alpers’ disease and allow timely avoidance of anti-seizure medication that can trigger liver failure.

Case Report Pages 230-232

Wernicke Encephalopathy in a Non-Alcoholic Obese Adolescent: A Case Report

Authors: Guyu Li, Anissa Amilhamja, Shariadne Lao and Mary Huckabee

Abstract: Wernicke encephalopathy (WE) is a life-threatening condition caused by a deficiency in thiamine, also known as Vitamin B1. WE is known to occur mainly in adult patients with heavy alcohol use. However, it is also seen in all age groups with prolonged severe malnutrition, high-calorie malnutrition, and extended fasting [1-4]. WE tends to be more common in low-income countries and is often under diagnosed in high-income countries like the U.S, especially in previously healthy adolescents.

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